α,ω-disuccinimidyl dodecaethylene glycol

Name	Bis-PE21- NHS ester
Synonyms	BIS-PEG9-NHS NHS-PEG24-NHS NHS-PEG16-NHS Bis-PE21- NHS ester Bis-PEG21-NHS Ester α,ω-disuccinimidyl octaethylene glycol α,ω-disuccinimidyl nonaethylene glycol α,ω-disuccinimidyl dodecaethylene glycol
CAS	1008402-79-6

Molecular Formula	C30H48N2O17
Molar Mass	708.71
Density	1.31±0.1 g/cm3(Predicted)
Boling Point	737.0±70.0 °C(Predicted)
Appearance	solid or viscous liquid
Storage Condition	-20°C
In vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	Bis-PEG9-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Bis-PEG9-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG9-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs).
target	Cleavable PEGs Alkyl/ether
in vitro research	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 21:11:58

Product Name: Bis-PE21- NHS ester Visit Supplier Webpage Request for quotation
CAS: 1008402-79-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Bis-PE21- NHS ester Visit Supplier Webpage Request for quotation
CAS: 1008402-79-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

α,ω-disuccinimidyl dodecaethylene glycol Request for Quotation